Anks1 | ankyrin repeat and SAM domain containing 1

GeneMGI:2446180Synonyms: Odin

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Vision/eye Behavior/neurological Skeleton Mortality/aging Cardiovascular system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



preweaning lethality, incomplete penetrance	3 supporting datasets	Anks1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
increased bone mineral density	1 supporting dataset	Anks1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.43x10^-5
increased bone mineral content	2 supporting datasets	Anks1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.43x10^-10
abnormal retina blood vessel morphology	1 supporting dataset	Anks1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.17x10^-5
thin ventricular wall	1 supporting dataset	Anks1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.44x10^-5
decreased thigmotaxis	2 supporting datasets	Anks1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.53x10^-5
limb grasping	1 supporting dataset	Anks1^em1(IMPC)Bay	heterozygote	Early adult	2.15x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Anks1.

Associated images

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Histopathology

There is no histopathology data found for Anks1.

IMPC related publications

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External links

No external links available for Anks1.

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*Anks1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Anks1^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Anks1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Anks1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Anks1^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Anks1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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