Farp1 | FERM, ARH/RhoGEF and pleckstrin domain protein 1

GeneMGI:2446173Synonyms: Cdep

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetFarp1tm1b(EUCOMM)HmguhomozygoteEarly adult5.86x10-7 
increased startle reflex1 supporting datasetFarp1tm1b(EUCOMM)HmguhomozygoteEarly adult7.68x10-8 
abnormal vitreous body morphology1 supporting datasetFarp1tm1b(EUCOMM)HmguhomozygoteEarly adult1.27x10-5 
increased fasting circulating glucose level1 supporting datasetFarp1tm1b(EUCOMM)HmguhomozygoteEarly adult7.81x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Farp1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Farp1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Farp1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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