Bms1 | BMS1, ribosome biogenesis factor

GeneMGI:2446132Synonyms: Bms1l

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Vision/eye Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal coat/hair pigmentation	6 supporting datasets	Bms1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.8x10^-5
abnormal lens morphology	3 supporting datasets	Bms1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.88x10^-11
abnormal retina morphology	1 supporting dataset	Bms1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	6.93x10^-6
cataract	1 supporting dataset	Bms1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.79x10^-10
decreased circulating sodium level	1 supporting dataset	Bms1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	9.26x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Bms1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bms1.

Associated images

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Histopathology

There is no histopathology data found for Bms1.

IMPC related publications

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External links

No external links available for Bms1.

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*Bms1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Bms1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Bms1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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