Klhl3 | kelch-like 3

GeneMGI:2445185Synonyms: 7530408C15Rik, EG627648

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system Cardiovascular system

15 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

increased circulating potassium level1 supporting datasetKlhl3tm1b(KOMP)WtsihomozygoteEarly adult4.21x10-20 
increased circulating alkaline phosphatase level1 supporting datasetKlhl3tm1b(KOMP)WtsihomozygoteEarly adult4.06x10-6 
decreased hemoglobin content1 supporting datasetKlhl3tm1b(KOMP)WtsihomozygoteEarly adult6.57x10-8 
increased heart weight1 supporting datasetKlhl3tm1b(KOMP)WtsihomozygoteEarly adult5.73x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Klhl3tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Klhl3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Klhl3tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Klhl3tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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