Wdr41 | WD repeat domain 41

GeneMGI:2445123Synonyms: MSTP048, B830029I03Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin1 supporting datasetWdr41em1(IMPC)JhomozygoteEarly adult1.02x10-27 
hyperactivity5 supporting datasetsWdr41em1(IMPC)JhomozygoteEarly adult1.37x10-6 
decreased grip strength1 supporting datasetWdr41em1(IMPC)JhomozygoteEarly adult3.65x10-5 
increased circulating HDL cholesterol level1 supporting datasetWdr41em1(IMPC)JhomozygoteEarly adult3.34x10-5 
decreased mean corpuscular volume1 supporting datasetWdr41em1(IMPC)JhomozygoteEarly adult2.48x10-16 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Wdr41em1(IMPC)JExon Deletionmouse
Wdr41tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Wdr41tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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