Dhx33 | DEAH-box helicase 33

GeneMGI:2445102Synonyms: Ddx33, 3110057P17Rik, +2 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased circulating thyroxine level1 supporting datasetDhx33tm1b(KOMP)WtsiheterozygoteEarly adult4.69x10-5 
prenatal lethality prior to heart atrial septation1 supporting datasetDhx33tm1b(KOMP)WtsihomozygoteE15.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetDhx33tm1b(KOMP)WtsihomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetDhx33tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dhx33tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dhx33tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Dhx33tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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