Nrros | negative regulator of reactive oxygen species

GeneMGI:2445095Synonyms: Lrrc33, E430025L02Rik

Physiological systems

10 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Behavior/neurological

9 No significant impact

14 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased thigmotaxis1 supporting datasetNrrosem1(IMPC)HhomozygoteEarly adult1.31x10-5 
hyperactivity8 supporting datasetsNrrosem1(IMPC)HhomozygoteEarly adult1.42x10-40 
abnormal gait1 supporting datasetNrrosem1(IMPC)HhomozygoteEarly adult1.29x10-19 
decreased locomotor activity2 supporting datasetsNrrosem1(IMPC)HhomozygoteEarly adult1.01x10-6 
increased anxiety-related response1 supporting datasetNrrosem1(IMPC)HhomozygoteEarly adult3.73x10-6 
abnormal behavior1 supporting datasetNrrosem1(IMPC)HhomozygoteEarly adult1.31x10-5 
limb grasping1 supporting datasetNrrosem1(IMPC)HhomozygoteEarly adult4.05x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nrrosem1(IMPC)HIndelmouse
Nrrosem2(IMPC)HIndelmouse
Nrrostm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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