Ccbe1 | collagen and calcium binding EGF domains 1
Physiological systems
22 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Embryo Vision/eye Liver/biliary system Mortality/aging Cardiovascular system Craniofacial
14 No significant impact
2 Not tested
Data collections
Gene metrics:16Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged uterus | 1 supporting dataset | Ccbe1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| pale liver | 1 supporting dataset | Ccbe1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| small liver | 1 supporting dataset | Ccbe1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| edema | 1 supporting dataset | Ccbe1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| microphthalmia | 1 supporting dataset | Ccbe1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal placenta morphology | 1 supporting dataset | Ccbe1em1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Ccbe1em1(IMPC)Mbp | heterozygote | Early adult | 2.73x10-5 | ||
| abnormal uterus morphology | 1 supporting dataset | Ccbe1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Ccbe1em1(IMPC)Mbp | heterozygote | Early adult | 3.36x10-8 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Ccbe1em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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External links
No external links available for Ccbe1.
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| Ccbe1em1(IMPC)Mbp | Exon Deletion | | mouse |
| Ccbe1tm46161(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |