Rsbn1 | rosbin, round spermatid basic protein 1

GeneMGI:2444993Synonyms: C230004D03Rik, Rsbp

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Adipose tissue Growth/size/body region Behavior/neurological Skeleton Mortality/aging

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal bone structure	1 supporting dataset	Rsbn1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.32x10^-5
decreased lean body mass	1 supporting dataset	Rsbn1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	8.63x10^-5
abnormal locomotor behavior	1 supporting dataset	Rsbn1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.46x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Rsbn1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased total body fat amount	1 supporting dataset	Rsbn1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.59x10^-5
increased circulating cholesterol level	1 supporting dataset	Rsbn1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.13x10^-5
abnormal seminal vesicle morphology	1 supporting dataset	Rsbn1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rsbn1.

Associated images

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Histopathology

There is no histopathology data found for Rsbn1.

IMPC related publications

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External links

No external links available for Rsbn1.

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*Rsbn1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rsbn1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rsbn1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Rsbn1^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Rsbn1^{tm3e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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