Ift56 | intraflagellar transport 56

GeneMGI:2444853Synonyms: hydrocephalic-polydactyl, 9430097H08Rik, +3 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Growth/size/body region Limbs/digits/tail Digestive/alimentary Behavior/neurological Craniofacial Mortality/aging

14 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetIft56em1(IMPC)JhomozygoteEarly adultN/A * 
no spontaneous movement1 supporting datasetIft56em1(IMPC)JhomozygoteE18.5N/A * 
polydactyly1 supporting datasetIft56em1(IMPC)JhomozygoteE18.5N/A * 
no spontaneous movement1 supporting datasetIft56em1(IMPC)JheterozygoteE18.5N/A * 
abnormal body wall morphology1 supporting datasetIft56em1(IMPC)JhomozygoteE18.5N/A * 
cleft palate1 supporting datasetIft56em1(IMPC)JhomozygoteE18.5N/A * 
increased grip strength1 supporting datasetIft56em1(IMPC)JheterozygoteEarly adult2.17x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ift56em1(IMPC)JExon Deletionmouse
Ift56tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ift56tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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