Ift56 | intraflagellar transport 56
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Growth/size/body region Limbs/digits/tail Digestive/alimentary Behavior/neurological Craniofacial Mortality/aging
14 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Ift56em1(IMPC)J | homozygote | Early adult | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Ift56em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| polydactyly | 1 supporting dataset | Ift56em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Ift56em1(IMPC)J | heterozygote | E18.5 | N/A * | ||
| abnormal body wall morphology | 1 supporting dataset | Ift56em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| cleft palate | 1 supporting dataset | Ift56em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| increased grip strength | 1 supporting dataset | Ift56em1(IMPC)J | heterozygote | Early adult | 2.17x10-5 |
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Human diseases caused by Ift56 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Ift56.
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| Ift56em1(IMPC)J | Exon Deletion | | mouse |
| Ift56tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ift56tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |