Negr1 | neuronal growth regulator 1
Physiological systems
21 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Nervous system Vision/eye Behavior/neurological Skeleton
17 No significant impact
3 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| decreased grip strength | 4 supporting datasets | Negr1tm1b(KOMP)Wtsi | homozygote | Early adult | 1.76x10-7 | ||
| decreased brain weight | 1 supporting dataset | Negr1tm1b(KOMP)Wtsi | homozygote | Early adult | 2.74x10-6 | ||
| hyperactivity | 1 supporting dataset | Negr1tm1b(KOMP)Wtsi | homozygote | Early adult | 1.9x10-8 | ||
| decreased bone mineral density | 1 supporting dataset | Negr1tm1b(KOMP)Wtsi | homozygote | Early adult | 4.08x10-5 | ||
| abnormal behavior | 1 supporting dataset | Negr1tm1b(KOMP)Wtsi | homozygote | Early adult | 4.72x10-18 | ||
| decreased thigmotaxis | 1 supporting dataset | Negr1tm1b(KOMP)Wtsi | homozygote | Early adult | 5.02x10-18 | ||
| abnormal eye morphology | 1 supporting dataset | Negr1tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| decreased bone mineral content | 1 supporting dataset | Negr1tm1b(KOMP)Wtsi | homozygote | Early adult | 4.3x10-5 |
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External links
No external links available for Negr1.
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| Negr1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Negr1tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Negr1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Negr1tm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |