Prss35 | serine protease 35

GeneMGI:2444800Synonyms: 6030424L22Rik

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

12 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal spleen morphology	2 supporting datasets	Prss35^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Prss35^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
kyphosis	1 supporting dataset	Prss35^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.53x10^-5
increased circulating chloride level	1 supporting dataset	Prss35^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.12x10^-5
small testis	1 supporting dataset	Prss35^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Prss35^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
hydrometra	1 supporting dataset	Prss35^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased locomotor activity	1 supporting dataset	Prss35^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.26x10^-5
abnormal thymus morphology	1 supporting dataset	Prss35^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Prss35^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prss35.

Associated images

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Histopathology

There is no histopathology data found for Prss35.

IMPC related publications

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External links

No external links available for Prss35.

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*Prss35^{em1(IMPC)Ccpcz}*	Inter-exon deletion	‌	mouse
*Prss35^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Prss35^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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