Klhl42 | kelch-like 42

GeneMGI:2444786Synonyms: Klhdc5, C230080I20Rik

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Hematopoietic system Skeleton

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased lean body mass1 supporting datasetKlhl42tm1b(EUCOMM)HmguhomozygoteEarly adult4.95x10-5 
thrombocytosis1 supporting datasetKlhl42tm1b(EUCOMM)HmguhomozygoteEarly adult9.21x10-7 
increased bone mineral content1 supporting datasetKlhl42tm1b(EUCOMM)HmguhomozygoteEarly adult4.52x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Klhl42tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Klhl42tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Klhl42tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Klhl42tm412839(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Klhl42tm460883(L1L2_GT2_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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