Fbxo38 | F-box protein 38

GeneMGI:2444639Synonyms: 6030410I24Rik, SP329

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:14Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity4 supporting datasetsFbxo38em2(IMPC)MarchomozygoteEarly adult2.14x10-6 
decreased body length1 supporting datasetFbxo38em2(IMPC)MarchomozygoteEarly adult5.03x10-7 
increased leukocyte cell number1 supporting datasetFbxo38em2(IMPC)MarchomozygoteEarly adult1.09x10-5 
decreased bone mineral density1 supporting datasetFbxo38em2(IMPC)MarchomozygoteEarly adult1.19x10-5 
increased lymphocyte cell number1 supporting datasetFbxo38em2(IMPC)MarchomozygoteEarly adult1.04x10-5 
increased red blood cell distribution width1 supporting datasetFbxo38em2(IMPC)MarchomozygoteEarly adult8.89x10-18 
small liver1 supporting datasetFbxo38em2(IMPC)MarchomozygoteEarly adultN/A * 
male infertility1 supporting datasetFbxo38em2(IMPC)MarchomozygoteEarly adultN/A * 
increased heart rate1 supporting datasetFbxo38em2(IMPC)MarchomozygoteEarly adult3.08x10-5 
increased basophil cell number1 supporting datasetFbxo38em2(IMPC)MarchomozygoteEarly adult9.67x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fbxo38em2(IMPC)MarcDeletionmouse
Fbxo38tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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