Kctd3 | potassium channel tetramerisation domain containing 3

GeneMGI:2444629Synonyms: 4930438A20Rik, NY-REN-45, +1 more

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Vision/eye Hematopoietic system Mortality/aging Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Kctd3^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Kctd3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Kctd3^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Kctd3^em1(IMPC)Tcp	homozygote	E15.5	N/A ^*
edema	1 supporting dataset	Kctd3^em1(IMPC)Tcp	homozygote	E15.5	N/A ^*
decreased mean corpuscular hemoglobin	1 supporting dataset	Kctd3^em1(IMPC)Tcp	heterozygote	Early adult	8.68x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kctd3.

Associated images

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Histopathology

There is no histopathology data found for Kctd3.

IMPC related publications

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External links

No external links available for Kctd3.

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*Kctd3^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Kctd3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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