Ipo8 | importin 8

GeneMGI:2444611Synonyms: Ranbp8, 6230418K12Rik, +3 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Nervous system Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

abnormal optic disk morphology1 supporting datasetIpo8tm1.1(KOMP)VlcghomozygoteEarly adult7.89x10-8 
decreased grip strength1 supporting datasetIpo8tm1.1(KOMP)VlcghomozygoteEarly adult2.56x10-5 
cataract1 supporting datasetIpo8tm1.1(KOMP)VlcghomozygoteEarly adult8.66x10-5 
abnormal retina blood vessel morphology2 supporting datasetsIpo8tm1.1(KOMP)VlcghomozygoteEarly adult4x10-5 
increased mean corpuscular hemoglobin1 supporting datasetIpo8tm1.1(KOMP)VlcgheterozygoteEarly adult1.55x10-5 
decreased exploration in new environment1 supporting datasetIpo8tm1.1(KOMP)VlcghomozygoteEarly adult1.84x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Ipo8tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
mouse
Ipo8tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter