Pptc7 | PTC7 protein phosphatase homolog

GeneMGI:2444593Synonyms: 9130017A15Rik

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Integument Embryo Growth/size/body region Behavior/neurological Mortality/aging

16 No significant impact

3 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues

Phenotypes

unresponsive to tactile stimuli1 supporting datasetPptc7tm1b(EUCOMM)HmguhomozygoteE18.5N/A * 
unresponsive to tactile stimuli1 supporting datasetPptc7tm1b(EUCOMM)HmguheterozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsPptc7tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal embryo size1 supporting datasetPptc7tm1b(EUCOMM)HmguhomozygoteE18.5N/A * 
abnormal coat appearance2 supporting datasetsPptc7tm1b(EUCOMM)HmguheterozygoteEarly adult7.48x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pptc7tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Pptc7tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Pptc7tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Pptc7tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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