Abi3bp | ABI family member 3 binding protein
Physiological systems
21 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Mortality/aging Craniofacial
14 No significant impact
3 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| increased red blood cell distribution width | 1 supporting dataset | Abi3bptm1e.1(KOMP)Mbp | homozygote | Early adult | 4.82x10-15 | ||
| increased mean platelet volume | 1 supporting dataset | Abi3bptm1e.1(KOMP)Mbp | homozygote | Early adult | 9.27x10-5 | ||
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Abi3bptm1e.1(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| decreased grip strength | 1 supporting dataset | Abi3bptm1e.1(KOMP)Mbp | homozygote | Early adult | 6.9x10-5 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Abi3bptm1e.1(KOMP)Mbp | homozygote | Early adult | 9.63x10-5 | ||
| abnormal tooth morphology | 1 supporting dataset | Abi3bptm1e.1(KOMP)Mbp | homozygote | Early adult | 6.69x10-5 |
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External links
No external links available for Abi3bp.
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| Abi3bptm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Abi3bptm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Abi3bptm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell mouse |
| Abi3bptm1e.1(KOMP)Mbp | Promoter excision from Targeted, non-conditional allele | | mouse |