Mtcl2 | microtubule crosslinking factor 2

GeneMGI:2444575Synonyms: 9830001H06Rik, D430036N24Rik, +1 more

Physiological systems

7 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Vision/eye

6 No significant impact

17 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



decreased total retina thickness	2 supporting datasets	Mtcl2^em1(IMPC)Bay	homozygote	Early adult	5.59x10^-11
abnormal retina outer nuclear layer morphology	2 supporting datasets	Mtcl2^em1(IMPC)Bay	homozygote	Early adult	1.27x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mtcl2.

Associated images

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Histopathology

There is no histopathology data found for Mtcl2.

IMPC related publications

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External links

No external links available for Mtcl2.

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*Mtcl2^em1(IMPC)Bay*	Intra-exon deletion	‌	mouse
*Mtcl2^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Mtcl2^{tm464023(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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