Mtcl2 | microtubule crosslinking factor 2

GeneMGI:2444575Synonyms: 9830001H06Rik, D430036N24Rik, +1 more

Physiological systems

7 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Vision/eye

6 No significant impact

17 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased total retina thickness2 supporting datasetsMtcl2em1(IMPC)BayhomozygoteEarly adult5.59x10-11 
abnormal retina outer nuclear layer morphology2 supporting datasetsMtcl2em1(IMPC)BayhomozygoteEarly adult1.27x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Mtcl2em1(IMPC)BayIntra-exon deletionmouse
Mtcl2tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Mtcl2tm464023(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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