Usp43 | ubiquitin specific peptidase 43

GeneMGI:2444541Synonyms: C630032K07Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hearing/vestibular/ear Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response1 supporting datasetUsp43em1(IMPC)MarchomozygoteEarly adult8.75x10-5 
decreased grip strength1 supporting datasetUsp43em1(IMPC)MarchomozygoteEarly adult7.99x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Usp43em1(IMPC)MarcDeletionmouse
Usp43tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Usp43tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Usp43tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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