Phf20l1 | PHD finger protein 20-like 1

GeneMGI:2444412Synonyms: E130113K22Rik, CGI-72

Physiological systems

17 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Immune system Adipose tissue Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

7 No significant impact

7 Not tested

Gene metrics:18Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased freezing behavior2 supporting datasetsPhf20l1em1(IMPC)TcphomozygoteEarly adult1.41x10-7 
decreased body length1 supporting datasetPhf20l1em1(IMPC)TcphomozygoteEarly adult3.28x10-8 
increased mean corpuscular hemoglobin1 supporting datasetPhf20l1em1(IMPC)TcphomozygoteEarly adult1.24x10-7 
increased mean corpuscular volume1 supporting datasetPhf20l1em1(IMPC)TcphomozygoteEarly adult5.17x10-7 
increased lean body mass1 supporting datasetPhf20l1em1(IMPC)TcphomozygoteEarly adult7.15x10-5 
increased mean platelet volume1 supporting datasetPhf20l1em1(IMPC)TcphomozygoteEarly adult5.28x10-6 
short tibia1 supporting datasetPhf20l1em1(IMPC)TcphomozygoteEarly adult7.79x10-6 
abnormal retina morphology1 supporting datasetPhf20l1em1(IMPC)TcphomozygoteEarly adult4.35x10-7 
enlarged lymph nodes1 supporting datasetPhf20l1em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal sternum morphology1 supporting datasetPhf20l1em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Phf20l1em1(IMPC)TcpExon Deletionmouse
Phf20l1tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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