Phf20l1 | PHD finger protein 20-like 1
Physiological systems
17 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Immune system Adipose tissue Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system
7 No significant impact
7 Not tested
Data collections
Gene metrics:18Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased freezing behavior | 2 supporting datasets | Phf20l1em1(IMPC)Tcp | homozygote | Early adult | 1.41x10-7 | ||
| decreased body length | 1 supporting dataset | Phf20l1em1(IMPC)Tcp | homozygote | Early adult | 3.28x10-8 | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Phf20l1em1(IMPC)Tcp | homozygote | Early adult | 1.24x10-7 | ||
| increased mean corpuscular volume | 1 supporting dataset | Phf20l1em1(IMPC)Tcp | homozygote | Early adult | 5.17x10-7 | ||
| increased lean body mass | 1 supporting dataset | Phf20l1em1(IMPC)Tcp | homozygote | Early adult | 7.15x10-5 | ||
| increased mean platelet volume | 1 supporting dataset | Phf20l1em1(IMPC)Tcp | homozygote | Early adult | 5.28x10-6 | ||
| short tibia | 1 supporting dataset | Phf20l1em1(IMPC)Tcp | homozygote | Early adult | 7.79x10-6 | ||
| abnormal retina morphology | 1 supporting dataset | Phf20l1em1(IMPC)Tcp | homozygote | Early adult | 4.35x10-7 | ||
| enlarged lymph nodes | 1 supporting dataset | Phf20l1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal sternum morphology | 1 supporting dataset | Phf20l1em1(IMPC)Tcp | homozygote | Early adult | N/A * |
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Human diseases caused by Phf20l1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Phf20l1.
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| Phf20l1em1(IMPC)Tcp | Exon Deletion | | mouse |
| Phf20l1tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |