Disp3 | dispatched RND transporter family member 3

GeneMGI:2444403Synonyms: Ptchd2, G630052C06Rik

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Hematopoietic system Skeleton Cardiovascular system Renal/urinary system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal heart morphology	1 supporting dataset	Disp3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal lymph node morphology	2 supporting datasets	Disp3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Disp3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
enlarged spleen	2 supporting datasets	Disp3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Disp3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged lymph nodes	2 supporting datasets	Disp3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Disp3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal uterus morphology	1 supporting dataset	Disp3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Disp3^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
increased bone mineral content	1 supporting dataset	Disp3^em1(IMPC)Mbp	homozygote	Early adult	2.62x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Disp3.

Associated images

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Histopathology

There is no histopathology data found for Disp3.

IMPC related publications

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External links

No external links available for Disp3.

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*Disp3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Disp3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Disp3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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