Fsd2 | fibronectin type III and SPRY domain containing 2

GeneMGI:2444310Synonyms: Spryd1, 9830160G03Rik

Physiological systems

20 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

9 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:24Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal ovary morphology	1 supporting dataset	Fsd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Fsd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Fsd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Fsd2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged ovary	1 supporting dataset	Fsd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
cornea opacity	1 supporting dataset	Fsd2^em1(IMPC)Mbp	homozygote	Late adult	8.89x10^-5
abnormal lymph node morphology	1 supporting dataset	Fsd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*
shortened QT interval	1 supporting dataset	Fsd2^em1(IMPC)Mbp	homozygote	Late adult	5.37x10^-5
increased grip strength	1 supporting dataset	Fsd2^em1(IMPC)Mbp	homozygote	Middle aged adult	1.2x10^-5
hydrometra	1 supporting dataset	Fsd2^em1(IMPC)Mbp	homozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fsd2.

Associated images

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Histopathology

There is no histopathology data found for Fsd2.

IMPC related publications

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External links

No external links available for Fsd2.

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*Fsd2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Fsd2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fsd2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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