Ubn2 | ubinuclein 2

GeneMGI:2444236Synonyms: D130059P03Rik, 2900060J04Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

11 Significantly impacted by the knock-out

 Reproductive system Integument Embryo Growth/size/body region Digestive/alimentary Nervous system Vision/eye Hematopoietic system Behavior/neurological Craniofacial Mortality/aging

8 No significant impact

5 Not tested

Gene metrics:16Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal facial morphology2 supporting datasetsUbn2em1(IMPC)TcphomozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsUbn2em1(IMPC)TcphomozygoteEarly adultN/A * 
male infertility1 supporting datasetUbn2em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal eyelid fusion1 supporting datasetUbn2em1(IMPC)TcphomozygoteE18.5N/A * 
decreased mean corpuscular hemoglobin concentration1 supporting datasetUbn2em1(IMPC)TcpheterozygoteEarly adult9.21x10-5 
abnormal head shape1 supporting datasetUbn2em1(IMPC)TcphomozygoteE18.5N/A * 
abnormal head size1 supporting datasetUbn2em1(IMPC)TcphomozygoteE18.5N/A * 
protruding tongue1 supporting datasetUbn2em1(IMPC)TcphomozygoteE18.5N/A * 
pallor1 supporting datasetUbn2em1(IMPC)TcphomozygoteE18.5N/A * 
anophthalmia1 supporting datasetUbn2em1(IMPC)TcphomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ubn2em1(IMPC)TcpExon Deletionmouse
Ubn2tm210826(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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