Alg6 | ALG6 alpha-1,3-glucosyltransferase
Physiological systems
21 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Immune system Integument Embryo Growth/size/body region Behavior/neurological Mortality/aging Renal/urinary system
14 No significant impact
3 Not tested
Data collections
Gene metrics:11Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
preweaning lethality, complete penetrance | 3 supporting datasets | Alg6em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
enlarged urinary bladder | 1 supporting dataset | Alg6em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
embryonic growth retardation | 1 supporting dataset | Alg6em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
decreased exploration in new environment | 1 supporting dataset | Alg6em1(IMPC)Tcp | heterozygote | Early adult | 4.44x10-6 | ||
abnormal allantois morphology | 1 supporting dataset | Alg6em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
abnormal skin morphology | 1 supporting dataset | Alg6em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
enlarged lymph nodes | 1 supporting dataset | Alg6em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
abnormal embryo size | 1 supporting dataset | Alg6em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
abnormal embryo development | 1 supporting dataset | Alg6em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
prenatal lethality prior to heart atrial septation | 1 supporting dataset | Alg6em1(IMPC)Tcp | homozygote | E15.5 | N/A * |
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External links
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Alg6em1(IMPC)Tcp | Exon Deletion | | mouse |
Alg6tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Alg6tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |