Ankrd52 | ankyrin repeat domain 52

GeneMGI:2444029Synonyms: G431002C21Rik

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Immune system Embryo Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Mortality/aging

11 No significant impact

5 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral content1 supporting datasetAnkrd52em1(IMPC)JheterozygoteEarly adult6.3x10-5 
anophthalmia1 supporting datasetAnkrd52em1(IMPC)JhomozygoteE18.5N/A * 
microphthalmia1 supporting datasetAnkrd52em1(IMPC)JhomozygoteE18.5N/A * 
abnormal vocalization1 supporting datasetAnkrd52em1(IMPC)JheterozygoteEarly adult2.42x10-10 
abnormal embryo size1 supporting datasetAnkrd52em1(IMPC)JhomozygoteE18.5N/A * 
decreased grip strength1 supporting datasetAnkrd52em1(IMPC)JheterozygoteEarly adult1.72x10-5 
increased leukocyte cell number1 supporting datasetAnkrd52em1(IMPC)JheterozygoteEarly adult6.01x10-6 
preweaning lethality, complete penetrance1 supporting datasetAnkrd52em1(IMPC)JhomozygoteEarly adultN/A * 
abnormal embryo size1 supporting datasetAnkrd52em1(IMPC)JheterozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ankrd52em1(IMPC)JExon Deletionmouse
Ankrd52tm78068(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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