Ankrd52 | ankyrin repeat domain 52
Physiological systems
19 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Mortality/aging
11 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased bone mineral content | 1 supporting dataset | Ankrd52em1(IMPC)J | heterozygote | Early adult | 6.3x10-5 | ||
| anophthalmia | 1 supporting dataset | Ankrd52em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| microphthalmia | 1 supporting dataset | Ankrd52em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| abnormal vocalization | 1 supporting dataset | Ankrd52em1(IMPC)J | heterozygote | Early adult | 2.42x10-10 | ||
| abnormal embryo size | 1 supporting dataset | Ankrd52em1(IMPC)J | homozygote | E18.5 | N/A * | ||
| decreased grip strength | 1 supporting dataset | Ankrd52em1(IMPC)J | heterozygote | Early adult | 1.72x10-5 | ||
| increased leukocyte cell number | 1 supporting dataset | Ankrd52em1(IMPC)J | heterozygote | Early adult | 6.01x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Ankrd52em1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Ankrd52em1(IMPC)J | heterozygote | E18.5 | N/A * |
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Human diseases caused by Ankrd52 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Ankrd52.
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| Ankrd52em1(IMPC)J | Exon Deletion | | mouse |
| Ankrd52tm78068(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |