Exoc3 | exocyst complex component 3

GeneMGI:2443972Synonyms: E430013E20Rik, Sec6l1, +1 more

Physiological systems

15 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region

12 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased total body fat amount1 supporting datasetExoc3tm2b(EUCOMM)HmguheterozygoteEarly adult3.44x10-6 
increased lean body mass1 supporting datasetExoc3tm2b(EUCOMM)HmguheterozygoteEarly adult5.35x10-7 
decreased fasting circulating glucose level1 supporting datasetExoc3tm2b(EUCOMM)HmguheterozygoteEarly adult3.82x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Exoc3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Exoc3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Exoc3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Exoc3tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Exoc3tm2b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Exoc3tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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