Bcorl1 | BCL6 co-repressor-like 1

GeneMGI:2443910Synonyms: 6720425J07Rik

Physiological systems

17 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Craniofacial

8 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:21Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



cataract	1 supporting dataset	Bcorl1^em1(IMPC)Tcp	hemizygote	Early adult	1.26x10^-7
abnormal snout morphology	1 supporting dataset	Bcorl1^em1(IMPC)Tcp	homozygote	Early adult	1.2x10^-5
decreased grip strength	1 supporting dataset	Bcorl1^em1(IMPC)Tcp	homozygote	Early adult	6.24x10^-8
increased mean corpuscular hemoglobin	1 supporting dataset	Bcorl1^em1(IMPC)Tcp	homozygote	Early adult	1.55x10^-15
decreased circulating HDL cholesterol level	1 supporting dataset	Bcorl1^em1(IMPC)Tcp	hemizygote	Early adult	3.32x10^-6
decreased circulating cholesterol level	1 supporting dataset	Bcorl1^em1(IMPC)Tcp	hemizygote	Early adult	4.01x10^-6
decreased grip strength	1 supporting dataset	Bcorl1^em1(IMPC)Tcp	hemizygote	Early adult	1.1x10^-5
cataract	1 supporting dataset	Bcorl1^em1(IMPC)Tcp	homozygote	Early adult	4.26x10^-6
increased mean platelet volume	1 supporting dataset	Bcorl1^em1(IMPC)Tcp	homozygote	Early adult	3x10^-9
abnormal lens morphology	1 supporting dataset	Bcorl1^em1(IMPC)Tcp	hemizygote	Early adult	1.05x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bcorl1.

Associated images

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Histopathology

There is no histopathology data found for Bcorl1.

IMPC related publications

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External links

No external links available for Bcorl1.

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*Bcorl1^em1(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Bcorl1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Bcorl1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Bcorl1^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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