Nell1 | NEL-like 1

GeneMGI:2443902Synonyms: l7R6, B230343H07Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Vision/eye Hematopoietic system Renal/urinary system

15 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

small adrenal glands1 supporting datasetNell1em1(IMPC)MbphomozygoteEarly adultN/A * 
cataract1 supporting datasetNell1em1(IMPC)MbphomozygoteEarly adult9.23x10-5 
abnormal vitreous body morphology1 supporting datasetNell1em1(IMPC)MbphomozygoteEarly adult7.3x10-5 
decreased mean corpuscular hemoglobin1 supporting datasetNell1em1(IMPC)MbphomozygoteEarly adult3.65x10-7 
abnormal lymph node morphology1 supporting datasetNell1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetNell1em1(IMPC)MbphomozygoteEarly adult5.3x10-5 
small kidney1 supporting datasetNell1em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nell1em1(IMPC)MbpExon Deletionmouse
Nell1tm43045(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Nell1tm43045(L1L2_st0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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