Aldh4a1 | aldehyde dehydrogenase 4 family, member A1

GeneMGI:2443883Synonyms: P5CDH, Ahd-1, +4 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance3 supporting datasetsAldh4a1em1(IMPC)BayhomozygoteEarly adultN/A * 
abnormal locomotor behavior1 supporting datasetAldh4a1em1(IMPC)BayheterozygoteEarly adult6.32x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Aldh4a1em1(IMPC)BayExon Deletionmouse
Aldh4a1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Aldh4a1tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Aldh4a1tm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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