Pcif1 | phosphorylated CTD interacting factor 1

GeneMGI:2443858Synonyms: F730014I05Rik, 2310022K11Rik

Physiological systems

12 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Nervous system Vision/eye Behavior/neurological Skeleton Mortality/aging

5 No significant impact

12 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased lean body mass	2 supporting datasets	Pcif1^em1(IMPC)Bay	homozygote	Early adult	7.32x10^-8
decreased total body fat amount	2 supporting datasets	Pcif1^em1(IMPC)Bay	homozygote	Early adult	9.53x10^-7
hyperactivity	1 supporting dataset	Pcif1^em1(IMPC)Bay	homozygote	Early adult	7.24x10^-5
decreased thigmotaxis	2 supporting datasets	Pcif1^em1(IMPC)Bay	homozygote	Early adult	5.55x10^-12
abnormal bone structure	1 supporting dataset	Pcif1^em1(IMPC)Bay	homozygote	Early adult	1.04x10^-6
abnormal optic disk morphology	1 supporting dataset	Pcif1^em1(IMPC)Bay	homozygote	Early adult	3.22x10^-5
decreased body length	1 supporting dataset	Pcif1^em1(IMPC)Bay	homozygote	Early adult	4.61x10^-5
abnormal eye anterior chamber depth	1 supporting dataset	Pcif1^em1(IMPC)Bay	homozygote	Early adult	7.07x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Pcif1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal retina morphology	2 supporting datasets	Pcif1^em1(IMPC)Bay	homozygote	Early adult	4.62x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pcif1.

Associated images

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Histopathology

There is no histopathology data found for Pcif1.

IMPC related publications

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External links

No external links available for Pcif1.

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*Pcif1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Pcif1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pcif1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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