Ppfia2 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

GeneMGI:2443834Synonyms: E130120L08Rik, Liprin-alpha2

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Nervous system Vision/eye Behavior/neurological Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina blood vessel morphology	2 supporting datasets	Ppfia2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.88x10^-6
abnormal optic disk morphology	1 supporting dataset	Ppfia2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.16x10^-6
abnormal gait	1 supporting dataset	Ppfia2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.08x10^-7
head bobbing	1 supporting dataset	Ppfia2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.1x10^-7
abnormal retina vasculature morphology	1 supporting dataset	Ppfia2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.36x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppfia2.

Associated images

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Histopathology

There is no histopathology data found for Ppfia2.

IMPC related publications

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External links

No external links available for Ppfia2.

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*Ppfia2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ppfia2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ppfia2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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