Stxbp5l | syntaxin binding protein 5-like

GeneMGI:2443815Synonyms: t2md1, insulin level locus 1, +4 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Behavior/neurological Skeleton

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased thigmotaxis	2 supporting datasets	Stxbp5l^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.76x10^-8
increased circulating alkaline phosphatase level	1 supporting dataset	Stxbp5l^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.05x10^-6
increased bone mineral content	1 supporting dataset	Stxbp5l^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.62x10^-6
hyperactivity	4 supporting datasets	Stxbp5l^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.56x10^-6
increased vertical activity	1 supporting dataset	Stxbp5l^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.93x10^-5
abnormal behavior	1 supporting dataset	Stxbp5l^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.76x10^-8
abnormal coat/ hair morphology	1 supporting dataset	Stxbp5l^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.67x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Stxbp5l.

Associated images

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Histopathology

There is no histopathology data found for Stxbp5l.

IMPC related publications

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External links

No external links available for Stxbp5l.

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*Stxbp5l^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Stxbp5l^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Stxbp5l^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Stxbp5l^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Stxbp5l^{tm43346(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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