Sipa1l1 | signal-induced proliferation-associated 1 like 1

GeneMGI:2443679Synonyms: 4931426N11Rik, Spar

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Behavior/neurological

17 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

increased vertical activity1 supporting datasetSipa1l1tm1.1(KOMP)VlcghomozygoteEarly adult3.97x10-55 
hyperactivity10 supporting datasetsSipa1l1tm1.1(KOMP)VlcghomozygoteEarly adult1.83x10-91 
abnormal behavior1 supporting datasetSipa1l1tm1.1(KOMP)VlcghomozygoteEarly adult1.73x10-6 
decreased grip strength2 supporting datasetsSipa1l1tm1.1(KOMP)VlcghomozygoteEarly adult1.5x10-5 
increased exploration in new environment1 supporting datasetSipa1l1tm1.1(KOMP)VlcghomozygoteEarly adult1.17x10-31 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sipa1l1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Sipa1l1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Sipa1l1tm299568(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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