Rreb1 | ras responsive element binding protein 1

GeneMGI:2443664Synonyms: sao, B930013M22Rik, +1 more

Physiological systems

15 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system

10 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating serum albumin level	1 supporting dataset	Rreb1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.52x10^-5
increased lean body mass	2 supporting datasets	Rreb1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.43x10^-5
increased red blood cell distribution width	1 supporting dataset	Rreb1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.06x10^-7
decreased hemoglobin content	1 supporting dataset	Rreb1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	7.13x10^-7
decreased total body fat amount	1 supporting dataset	Rreb1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.55x10^-5
decreased erythrocyte cell number	1 supporting dataset	Rreb1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.99x10^-7
decreased circulating calcium level	1 supporting dataset	Rreb1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.72x10^-6
increased leukocyte cell number	1 supporting dataset	Rreb1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.56x10^-5
decreased hematocrit	1 supporting dataset	Rreb1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.89x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rreb1.

Associated images

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Histopathology

There is no histopathology data found for Rreb1.

IMPC related publications

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External links

No external links available for Rreb1.

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*Rreb1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rreb1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rreb1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rreb1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Rreb1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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