Ccdc66 | coiled-coil domain containing 66

GeneMGI:2443639Synonyms: E230015L20Rik

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin concentration1 supporting datasetCcdc66em1(IMPC)MbphomozygoteEarly adult1.34x10-8 
impaired glucose tolerance1 supporting datasetCcdc66em1(IMPC)MbphomozygoteEarly adult9.04x10-5 
increased hematocrit1 supporting datasetCcdc66em1(IMPC)MbphomozygoteEarly adult9.74x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ccdc66em1(IMPC)MbpInter-exon deletionmouse
Ccdc66tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ccdc66tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Ccdc66tm379125(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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