Tmem203 | transmembrane protein 203

GeneMGI:2443597Synonyms: C730025P13Rik

Physiological systems

16 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Growth/size/body region Nervous system Vision/eye Behavior/neurological Cardiovascular system

9 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity7 supporting datasetsTmem203em1(IMPC)HhomozygoteEarly adult1.32x10-28 
increased heart weight1 supporting datasetTmem203em1(IMPC)HhomozygoteEarly adult5.11x10-8 
decreased prepulse inhibition2 supporting datasetsTmem203em1(IMPC)HhomozygoteEarly adult4.59x10-6 
decreased circulating cholesterol level1 supporting datasetTmem203em1(IMPC)HhomozygoteEarly adult4.65x10-9 
prolonged RR interval1 supporting datasetTmem203em1(IMPC)HhomozygoteEarly adult3.63x10-6 
decreased circulating HDL cholesterol level1 supporting datasetTmem203em1(IMPC)HhomozygoteEarly adult2.84x10-7 
increased circulating alkaline phosphatase level1 supporting datasetTmem203em1(IMPC)HhomozygoteEarly adult1.36x10-19 
male infertility1 supporting datasetTmem203em1(IMPC)HhomozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetTmem203em1(IMPC)HhomozygoteEarly adult4.32x10-5 
increased circulating calcium level1 supporting datasetTmem203em1(IMPC)HhomozygoteEarly adult2.63x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmem203em1(IMPC)HIndelmouse
Tmem203em2(IMPC)HIndelmouse
Tmem203tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell

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