Ccdc28a | coiled-coil domain containing 28A

GeneMGI:2443508Synonyms: 1700009P13Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Pigmentation Growth/size/body region Vision/eye Behavior/neurological Cardiovascular system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased grip strength	2 supporting datasets	Ccdc28a^{tm3b(EUCOMM)Wtsi}	homozygote	Late adult	3.62x10^-6
abnormal iris pigmentation	1 supporting dataset	Ccdc28a^{tm3b(EUCOMM)Wtsi}	homozygote	Early adult	1.45x10^-5
hyperactivity	1 supporting dataset	Ccdc28a^{tm3b(EUCOMM)Wtsi}	homozygote	Late adult	7.76x10^-7
increased lean body mass	1 supporting dataset	Ccdc28a^{tm3b(EUCOMM)Wtsi}	homozygote	Late adult	4.01x10^-5
male infertility	1 supporting dataset	Ccdc28a^{tm3b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
prolonged RR interval	1 supporting dataset	Ccdc28a^{tm3b(EUCOMM)Wtsi}	homozygote	Late adult	3.47x10^-5
limb grasping	1 supporting dataset	Ccdc28a^{tm3b(EUCOMM)Wtsi}	homozygote	Late adult	6.37x10^-7
decreased anxiety-related response	1 supporting dataset	Ccdc28a^{tm3b(EUCOMM)Wtsi}	homozygote	Late adult	1.11x10^-5
decreased vertical activity	1 supporting dataset	Ccdc28a^{tm3b(EUCOMM)Wtsi}	homozygote	Late adult	2x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ccdc28a.

Associated images

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Histopathology

There is no histopathology data found for Ccdc28a.

IMPC related publications

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External links

No external links available for Ccdc28a.

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*Ccdc28a^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ccdc28a^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Ccdc28a^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Ccdc28a^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ccdc28a^{tm3b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ccdc28a^{tm3e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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