Atf7 | activating transcription factor 7

GeneMGI:2443472Synonyms: 9430065F09Rik, 1110012F10Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Nervous system Vision/eye Behavior/neurological Skeleton

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased startle reflex	1 supporting dataset	Atf7^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	3.4x10^-18
persistence of hyaloid vascular system	1 supporting dataset	Atf7^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	1.2x10^-5
decreased prepulse inhibition	4 supporting datasets	Atf7^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	6.61x10^-15
increased bone mineral density	1 supporting dataset	Atf7^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	1.27x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atf7.

Associated images

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Histopathology

There is no histopathology data found for Atf7.

IMPC related publications

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External links

No external links available for Atf7.

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*Atf7^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Atf7^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Atf7^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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