Dgki | diacylglycerol kinase, iota

GeneMGI:2443430Synonyms: C130010K08Rik

Physiological systems

14 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Skeleton

11 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased body length1 supporting datasetDgkiem1(IMPC)WtsihomozygoteEarly adult3.22x10-5 
increased circulating glycerol level1 supporting datasetDgkiem1(IMPC)WtsihomozygoteEarly adult1.94x10-6 
decreased bone mineral content1 supporting datasetDgkiem1(IMPC)WtsihomozygoteEarly adult8.77x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dgkiem1(IMPC)WtsiExon Deletionmouse
Dgkitm43641(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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