Arhgap22 | Rho GTPase activating protein 22

GeneMGI:2443418Synonyms: B230341L19Rik, RHOGAP2

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating calcium level	1 supporting dataset	Arhgap22^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.12x10^-5
decreased circulating LDL cholesterol level	1 supporting dataset	Arhgap22^{tm1a(KOMP)Wtsi}	homozygote	Early adult	7.66x10^-8
increased mean corpuscular hemoglobin	1 supporting dataset	Arhgap22^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.98x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arhgap22.

Associated images

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Histopathology

There is no histopathology data found for Arhgap22.

IMPC related publications

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External links

No external links available for Arhgap22.

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*Arhgap22^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Arhgap22^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Arhgap22^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Arhgap22^{tm41944(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Arhgap22^{tm41944(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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