Trib1 | tribbles pseudokinase 1
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Integument Embryo Growth/size/body region Behavior/neurological Skeleton Mortality/aging
15 No significant impact
3 Not tested
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues
abnormal coat appearance | 1 supporting dataset | Trib1tm1b(KOMP)Wtsi | heterozygote | Early adult | 7.38x10-5 | ||
unresponsive to tactile stimuli | 1 supporting dataset | Trib1tm1b(KOMP)Wtsi | heterozygote | E18.5 | N/A * | ||
decreased bone mineral density | 1 supporting dataset | Trib1tm1b(KOMP)Wtsi | homozygote | Early adult | 2.49x10-9 | ||
abnormal skin coloration | 1 supporting dataset | Trib1tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.24x10-5 | ||
unresponsive to tactile stimuli | 1 supporting dataset | Trib1tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
abnormal coat appearance | 1 supporting dataset | Trib1tm1b(KOMP)Wtsi | homozygote | Early adult | 2.44x10-5 | ||
preweaning lethality, incomplete penetrance | 3 supporting datasets | Trib1tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
abnormal embryo size | 1 supporting dataset | Trib1tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * |
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External links
No external links available for Trib1.
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Trib1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Trib1tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Trib1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |