Lancl3 | LanC lantibiotic synthetase component C-like 3 (bacterial)

GeneMGI:2443335Synonyms: 6030463G20Rik

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Skeleton

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating serum albumin level1 supporting datasetLancl3em1(IMPC)HhemizygoteLate adult3.8x10-8 
decreased bone mineral density1 supporting datasetLancl3em1(IMPC)HhemizygoteLate adult7.12x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Lancl3em1(IMPC)HExon Deletionmouse
Lancl3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Lancl3tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Lancl3tm44266(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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