Dlgap2 | DLG associated protein 2

GeneMGI:2443181Synonyms: SAP90/PSD-95-associated protein 2, DAP2, +3 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased eosinophil cell number	2 supporting datasets	Dlgap2^{em1(IMPC)Mhzh}	homozygote	Early adult	4.47x10^-11
decreased lymphocyte cell number	1 supporting dataset	Dlgap2^{em1(IMPC)Mhzh}	homozygote	Early adult	6.54x10^-11
decreased locomotor activity	2 supporting datasets	Dlgap2^{em1(IMPC)Mhzh}	homozygote	Early adult	4x10^-5
increased fasting circulating glucose level	1 supporting dataset	Dlgap2^{em1(IMPC)Mhzh}	homozygote	Early adult	2.1x10^-8
increased neutrophil cell number	2 supporting datasets	Dlgap2^{em1(IMPC)Mhzh}	homozygote	Early adult	1.84x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dlgap2.

Associated images

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Histopathology

There is no histopathology data found for Dlgap2.

IMPC related publications

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External links

No external links available for Dlgap2.

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*Dlgap2^{em1(IMPC)Mhzh}*	Deletion	‌	mouse
*Dlgap2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dlgap2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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