Brinp3 | bone morphogenetic protein/retinoic acid inducible neural specific 3

GeneMGI:2443035Synonyms: Fam5c, B830045N13Rik

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Growth/size/body region Behavior/neurological Skeleton Cardiovascular system Renal/urinary system

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



rib fusion	1 supporting dataset	Brinp3^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.3x10^-5
lordosis	1 supporting dataset	Brinp3^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.49x10^-6
abnormal behavior	1 supporting dataset	Brinp3^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.43x10^-7
decreased body weight	1 supporting dataset	Brinp3^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.22x10^-9
abnormal rib morphology	1 supporting dataset	Brinp3^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.61x10^-5
abnormal vertebral arch morphology	1 supporting dataset	Brinp3^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.99x10^-6
abnormal urinary bladder morphology	1 supporting dataset	Brinp3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Brinp3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Brinp3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Brinp3^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Brinp3.

Associated images

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Histopathology

There is no histopathology data found for Brinp3.

IMPC related publications

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External links

No external links available for Brinp3.

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*Brinp3^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Brinp3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Brinp3^{tm42551(L1L2_st2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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