Ino80c | INO80 complex subunit C

GeneMGI:2443014Synonyms: D030070L09Rik

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Behavior/neurological Cardiovascular system Mortality/aging

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic growth retardation1 supporting datasetIno80cem1(IMPC)JhomozygoteE9.5N/A * 
abnormal tail morphology1 supporting datasetIno80cem1(IMPC)JhomozygoteE12.5N/A * 
abnormal embryo size1 supporting datasetIno80cem1(IMPC)JhomozygoteE12.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetIno80cem1(IMPC)JhomozygoteEarly adultN/A * 
abnormal hindbrain morphology1 supporting datasetIno80cem1(IMPC)JhomozygoteE12.5N/A * 
anophthalmia1 supporting datasetIno80cem1(IMPC)JhomozygoteE12.5N/A * 
eye hemorrhage1 supporting datasetIno80cem1(IMPC)JheterozygoteEarly adult6.92x10-5 
abnormal heart morphology1 supporting datasetIno80cem1(IMPC)JhomozygoteE9.5N/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetIno80cem1(IMPC)JhomozygoteE15.5N/A * 
increased vertical activity1 supporting datasetIno80cem1(IMPC)JheterozygoteEarly adult1.86x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ino80cem1(IMPC)JExon Deletionmouse
Ino80ctm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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