Trappc8 | trafficking protein particle complex 8

GeneMGI:2443008Synonyms: D030074E01Rik, Trs85, +1 more

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Endocrine/exocrine gland Vision/eye Hematopoietic system Cardiovascular system Mortality/aging

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina blood vessel morphology1 supporting datasetTrappc8em1(IMPC)TcpheterozygoteEarly adult9.8x10-7 
increased eosinophil cell number1 supporting datasetTrappc8em1(IMPC)TcpheterozygoteEarly adult5.18x10-6 
preweaning lethality, incomplete penetrance1 supporting datasetTrappc8em1(IMPC)TcphomozygoteEarly adultN/A * 
increased circulating alanine transaminase level1 supporting datasetTrappc8em1(IMPC)TcpheterozygoteEarly adult1.35x10-6 
abnormal retina vasculature morphology1 supporting datasetTrappc8em1(IMPC)TcpheterozygoteEarly adult9.47x10-7 
abnormal pancreas morphology1 supporting datasetTrappc8em1(IMPC)TcpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trappc8em1(IMPC)TcpExon Deletionmouse

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