Baz2b | bromodomain adjacent to zinc finger domain, 2B

GeneMGI:2442782Synonyms: 5830435C13Rik, D2Ertd794e

Physiological systems

15 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Immune system Integument Adipose tissue Growth/size/body region Hematopoietic system Skeleton

7 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal coat/hair pigmentation	2 supporting datasets	Baz2b^{em1(IMPC)Wtsi}	homozygote	Early adult	3.53x10^-5
increased total body fat amount	1 supporting dataset	Baz2b^{em1(IMPC)Wtsi}	homozygote	Early adult	3.08x10^-5
decreased circulating glucose level	1 supporting dataset	Baz2b^{em1(IMPC)Wtsi}	homozygote	Early adult	4.5x10^-5
decreased lean body mass	1 supporting dataset	Baz2b^{em1(IMPC)Wtsi}	homozygote	Early adult	7.04x10^-5
increased leukocyte cell number	1 supporting dataset	Baz2b^{em1(IMPC)Wtsi}	homozygote	Early adult	4.72x10^-10
decreased body length	1 supporting dataset	Baz2b^{em1(IMPC)Wtsi}	homozygote	Early adult	6.78x10^-5
decreased bone mineral density	1 supporting dataset	Baz2b^{em1(IMPC)Wtsi}	homozygote	Early adult	8.39x10^-12
decreased bone mineral content	1 supporting dataset	Baz2b^{em1(IMPC)Wtsi}	homozygote	Early adult	6.93x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Baz2b^{em1(IMPC)Wtsi}	homozygote	Early adult	7.63x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Baz2b.

Associated images

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Histopathology

There is no histopathology data found for Baz2b.

IMPC related publications

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External links

No external links available for Baz2b.

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*Baz2b^{em1(IMPC)Wtsi}*	Deletion	‌	mouse
*Baz2b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Baz2b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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