Cacna2d4 | calcium channel, voltage-dependent, alpha 2/delta subunit 4

GeneMGI:2442632Synonyms: 5730412N02Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological Cardiovascular system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity5 supporting datasetsCacna2d4em1(IMPC)JhomozygoteEarly adult1.01x10-7 
abnormal retina blood vessel morphology1 supporting datasetCacna2d4em1(IMPC)JhomozygoteEarly adult3.17x10-7 
abnormal retina morphology1 supporting datasetCacna2d4em1(IMPC)JhomozygoteEarly adult1.79x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cacna2d4em1(IMPC)JExon Deletionmouse
Cacna2d4tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cacna2d4tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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