Stk38 | serine/threonine kinase 38

GeneMGI:2442572Synonyms: 5830476G13Rik, 9530097A09Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hearing/vestibular/ear Hematopoietic system Mortality/aging Cardiovascular system

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased heart weight	1 supporting dataset	Stk38^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.4x10^-5
abnormal auditory brainstem response	2 supporting datasets	Stk38^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.67x10^-6
increased fasting circulating glucose level	1 supporting dataset	Stk38^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.42x10^-5
increased leukocyte cell number	1 supporting dataset	Stk38^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.5x10^-5
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Stk38^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.73x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Stk38^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Stk38.

Associated images

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Histopathology

There is no histopathology data found for Stk38.

IMPC related publications

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External links

No external links available for Stk38.

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*Stk38^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Stk38^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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